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| Product Code | Hep 3B2_1-7; HEP3B217; Hep 3B2; HEP-3B2; HEP3B2; Hep-3B; HEP-3B; Hep 3B; Hep3B; HEP3B |
| Species | Human |
| Cat.No | ABC-TC5585 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Liver |
| Disease | Hepatocellular Cancer |
| Storage | Liquid Nitrogen |
| Product Type | Human Liver Cancer Cell Lines |
Hep 3B is a human hepatoma cell line originally derived from liver tissue obtained from an 8-year-old Black patient with liver cancer.
These cells harbor an integrated hepatitis B virus genome and display an epithelial morphology. Notably, Hep3B cells possess tumorigenic properties in nude mice. Chromosomally, they maintain an average of 60 chromosomes per cell, with a predominant subtetraploid mode of 82. In terms of gene expression, this cell line exhibits the production of various proteins including alpha-fetoprotein (AFP), hepatitis B surface antigen (HBsAg), albumin, alpha-2-macroglobulin, alpha-1-antitrypsin, transferrin, alpha-1-antichymotrypsin, haptoglobin, ceruloplasmin, plasminogen complement (C3, C4), C3 activator, fibrinogen, alpha-1 acid glycoprotein, alpha-2-HS-glycoprotein, beta-lipoprotein, and retinol-binding protein.
Why choose Hep 3B from AcceGen?
Hep 3B cells from AcceGen offer exceptional viability and quality, cultivated under expert care in optimal conditions, ensuring sterility by being free of bacteria, fungi, and mycoplasma. Their identity is confirmed through STR analysis, and they are detected to express HBV, making them a reliable choice for various research applications.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
The Hep 3B cell line serves as a vital tool in biomedical research, particularly in elucidating the intricate relationship between HBV infection and the development of hepatocellular carcinoma. Additionally, these cells find widespread utility in drug metabolism and hepatotoxicity studies, offering insights into the effects of various compounds on the liver. Furthermore, Hep3B cells are valuable for investigating plasma protein biosynthesis and studying the interplay between the hepatitis B virus genome and tumorigenicity, making them indispensable for a range of experimental models and scientific inquiries.
