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Stem Cells

HighQC™ C57BL/6 Mouse Lung Mesenchymal Stem Cell

  • For research use only

Cat No.

ABC-SC0044T
Product Type

Animal Mesenchymal Stem Cells
Cell Type

Mesenchymal Stem Cell
Species

Mouse
Growth Conditions

37 ℃, 5% CO2
Source Organ

Lung
Disease

Normal
Storage

Liquid Nitrogen

HighQC™ C57BL/6 Mouse Lung MSCs enable studies of lung repair, mesenchymal lineage differentiation, and pulmonary fibrosis in mouse stem cell models.

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  • HighQC™ C57BL/6 Mouse Lung Mesenchymal Stem Cell
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Home | Stem Cells | Mesenchymal Stem Cells (MSC) | HighQC™ C57BL/6 Mouse Lung Mesenchymal Stem Cell

Description

HighQC™ C57BL/6 Mouse Lung Mesenchymal Stem Cells (MSCs) are derived from the lung tissues of adult C57BL/6 mice. The cells exhibit a characteristic fibroblast-like, spindle-shaped morphology in standard culture conditions. During lung injury, the bioactive lipid lysophosphatidic acid (LPA) is released from numerous cells, which activates the LPAR1 receptor on lung-resident MSCs (LR-MSCs), causing the LR-MSCs to migrate and differentiate into fibroblasts. These MSCs offer a biologically relevant tool for probing fibrotic mechanisms and immunomodulation in preclinical lung models. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from mycoplasma, fungi, yeast, and bacteria.

Product Code

HighQC™ C57BL/6 Mouse Lung Mesenchymal Stem Cell, C57BL/6 Lung MSC, C57-mL-MSC, Mouse Lung MSC
Species

Mouse
Cat.No

ABC-SC0044T
Product Category

Stem Cells
Size/Quantity

1 vial
Cell Type

Mesenchymal Stem Cell
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Lung
Disease

Normal
Storage

Liquid Nitrogen
Product Type

Animal Mesenchymal Stem Cells

Application

  • HighQC™ C57BL/6 Mouse Lung Mesenchymal Stem Cells serve as a physiologically relevant in vitro model for investigating pulmonary regenerative mechanisms and disease pathogenesis. These C57 mouse pulmonary mesenchymal cells are particularly valuable in murine models of chronic lung disease, enabling researchers to elucidate mesenchymal-immune interactions, immunomodulation, and fibrotic differentiation. This facilitates targeted studies of extracellular matrix (ECM) remodeling and epithelial-mesenchymal transition (EMT) in conditions such as idiopathic pulmonary fibrosis, thereby advancing therapeutic discovery for epithelial-mesenchymal crosstalk dysregulation.

Citation

When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
To succeed in cell culture
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To support a consistent result
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