HighQC™ Human Prostate Cancer Stem Cell

Description

HighQC™ Human Prostate Cancer Stem Cells (PCSCs) are derived from primary human prostate adenocarcinoma specimens. In vitro, PCSCs grow as non-adherent prostatospheres under serum-free, low-attachment conditions and display small, round to spindle-shaped morphology. They express established canonical cancer stem cell markers such as CD44 and CD133. Expression of pluripotency-linked transcription factors including OCT4, SOX2, and NANOG is also elevated in Human PCSCs, supporting their role in tumor initiation, progression, and therapy resistance. These molecular features align with castration-resistant phenotypes and have been implicated in prostate tumor relapse and metastasis. They retain stable growth characteristics over early passages, facilitating reproducible outcomes in long-term experimental protocols. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.