Primary Cells

Human Aortic Smooth Muscle Cells, Descending Aorta

  • For research use only

Cat No.

ABC-TC3497

Product Type

Vascular Cells

Cell Type

Smooth Muscle Cell

Species

Human

Growth Conditions

37 ℃, 5% CO2

Source Organ

Aorta

Disease

Normal

Storage

Liquid Nitrogen

Primary Human Aortic Smooth Muscle Cells were initiated from normal human descending aorta tissue.

Product Image

Description

Human Aortic Smooth Muscle Cells (HASMCs), Descending Aorta are primary cells isolated from human descending aorta tissue and cryopreserved at low passage. Belonging to the smooth muscle cell type, these cells exhibit characteristic spindle-shaped morphology and grow as adherent monolayers. These cells play a crucial role in maintaining the aorta’s structure and function, regulating vascular tone for blood pressure control, and are central to understanding the role of smooth muscle in aortic diseases. Pathologically, these cells are implicated in cardiovascular diseases including atherosclerosis, aortic aneurysms, and hypertension. HASMCs express smooth muscle α-actin. Repeated freezing and thawing should be avoided during culture. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

Human Descending Aorta Smooth Muscle Cells, Descending Aortic SMCs, Human Aortic SMCs Descending, Aorta Smooth Muscle Cells Human Descending, HAoSMCs Descending

Species

Human

Cat.No

ABC-TC3497

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Smooth Muscle Cell

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Aorta

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Vascular Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Human Aortic Smooth Muscle Cells (HASMCs) from the descending aorta serve as a physiologically relevant in vitro model to study vascular pathogenesis in conditions like hypertension, aortic aneurysm, and atherosclerosis. Their responsiveness to TGF-β signaling and MMP activity enables detailed investigation of extracellular matrix remodeling. Researchers can utilize them to reveal mechanisms of medial layer degradation and hypercontractility, which enables therapeutic screening of vasodilators and stent coatings targeting arterial stiffness and plaque destabilization in cardiovascular diseases.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Inquiring Human Aortic Smooth Muscle Cells, Descending Aorta

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

AcceGen Scroll Top Button