Human Astrocytes-Midbrain

Description

Human Astrocytes-Midbrain are primary cells isolated from human midbrain (mesencephalon tissue). Following primary culture, these cells are cryopreserved. These specialized glial cells exhibit stellate morphology and adherent growth in culture. Human Astrocytes-Midbrain play critical roles in the midbrain microenvironment by supporting neuronal survival, regulating neurotransmitter levels (particularly dopamine and glutamate homeostasis), mediating astrocyte-neuron communication, and sustaining midbrain astrocyte metabolism, and they are also linked to neurodegenerative diseases like Parkinson’s by neuroinflammatory modulation. Robust expression of glial fibrillary acidic protein (GFAP) is confirmed, validating their astrocytic identity. Repeated freezing and thawing should be avoided during culture. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.