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Human Cord Blood CD14+ Monocytes

  • BSL

    1

  • 135
Cord Blood CD14+ Monocytes are positively selected from mononuclear cells, using immunomagnetic CD14 MicroBeads.
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Home | Primary Cells | Human Primary Cells | Blood System Primary Cells | Human Cord Blood CD14+ Monocytes
Species

Human
Cat.No

ABC-TC3367
Quality Control

All cell lots test negative for HIV-1, HBV, HCV, mycoplasma, yeast, fungi, and other pathogens.
Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Monocyte
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Cord Blood
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Cord Blood Cells
Key Features

– Backed by AcceGen advanced technology

– Cryopreserved for highest viability and plating efficiency

– Quality-guaranteed for accurate results

– Timely technical support for best experimental outcomes

Description

Human Cord Blood CD14⁺ Monocytes are primary immune cells isolated from healthy human umbilical cord blood and belong to the monocyte lineage. Characterized by high CD14 expression and variable CD16, they display round or oval morphology, granular cytoplasm, and suspension growth. These non-proliferative cells are precursors to macrophages and dendritic cells, capable of phagocytosis, antigen presentation, and cytokine secretion (e.g., TNF-α, IL-6). Involved in host defense, inflammation, autoimmune diseases, and transplant immunology, they play a central role in both innate and adaptive immunity. These cells are express of CD14, CD16, and HLA-DR. Their responsiveness to pathogens makes them ideal for studying immune responses and monocyte-to-macrophage differentiation.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

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Application

  • Human Cord Blood CD14+ Monocytes can be used to study monocyte-macrophage differentiation, innate immune response, and inflammatory regulation mechanisms. They can also be used to study TLR signaling pathways, cell polarization (e.g., M1/M2 macrophages), and immune metabolic reprogramming mechanisms. In addition, CD14+ monocytes can be employed in the development cell-based therapies, such as the in vitro induction of anti-inflammatory macrophages for potential treatment of inflammatory diseases such as colitis.

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