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Primary Cells

Human Coronary Art Sm Mus Cells-Diabetic Type I

  • For research use only

Cat No.

ABC-TC3580
Product Type

Vascular Cells
Cell Type

Smooth Muscle Cell
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Coronary Artery Tissue
Disease

Type I Diabete
Storage

Liquid Nitrogen

Human Coronary Art Sm Mus Cells-Diabetic Type I, isolated from diabetic human donors,are ideal for studying cardiovascular disease and smooth muscle cells.

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  • Human Coronary Art Sm Mus Cells-Diabetic Type I
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Home | Primary Cells | Human Primary Cells | Blood System Primary Cells | Human Coronary Art Sm Mus Cells-Diabetic Type I

Description

Human Coronary Artery Smooth Muscle Cells-Diabetic Type I (HCASMC-DM1) are isolated from donors diagnosed with Type 1 Diabetes and cryopreserved at early passage to ensure optimal viability and performance. HCASMC-DM1 display a typical spindle-shaped morphology and grow in a monolayer. These cells express smooth muscle-specific markers including α-smooth muscle actin (α-SMA) and calponin. HCASMC-DM1 reflect pathological changes associated with Type 1 Diabetes, including altered proliferation, contractility, and extracellular matrix remodeling key contributors to diabetic vascular complications. These cells serve as a valuable model for studying the mechanisms of vascular dysfunction in Type 1 Diabetes. Repeated freeze-thaw cycles should be avoided during handling. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

Product Code

Human Coronary Artery Smooth Muscle Cells Type I Diabetes, HCASMCs T1DM, Coronary SMCs Diabetic Type I, Human Coronary Smooth Muscle Cells T1DM, Diabetic Type I Coronary SMCs
Species

Human
Cat.No

ABC-TC3580
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Smooth Muscle Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Coronary Artery Tissue
Disease

Type I Diabete
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Vascular Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Human coronary artery smooth muscle cells (Type 1 Diabetes) serve as a critical in vitro model to investigate the pathological changes in vascular smooth muscle associated with diabetes. These cells are widely used to study mechanisms of diabetic vascular remodeling, hyperplasia, and calcification. Their use contributes to understanding the progression of diabetic macrovascular complications and testing novel therapeutics aimed at preventing smooth muscle dysfunction in diabetic patients.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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