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Human Liver Microsomes-50 Donors (0.5 mL)

Product Name

Human Liver Microsomes-50 Donors (0.5 mL)

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Cat.No

ABC-TC3674

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Pooled Human Liver Microsomes provide a fully characterized, relevant, reliable and reproducible in vitro tool. Pooled of 50 donors give an economic way of deriving an accurate population representation and may be used to describe the metabolic profile of a drug or drug candidate in high-throughput assays as well as the following other uses:
Conduct studies of metabolic stability (% of original drug remaining over time)
Identify which cytochrome P450 (CYP) enzymes oxidize a drug candidate and which UDP-glucuronosyltransferase (UGT) enzymes are responsible for glucuronidation
Identify, quantify and characterize drug metabolites
Describe a drug’s metabolic pathways
Identify inhibition of cytochrome P450 (CYP) enzymes

Disease

Normal

Source Organ

Liver

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

For research use only

Growth Conditions

37 ℃, 5% CO2

Product Type

Hepatic Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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