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Primary Cells

Human Liver S9 Fraction-200 Donors (0.5 mL)

  • For research use only

Cat No.

ABC-TC3676
Product Type

Subcellular Fractions
Cell Type

Liver S9 Fraction
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Liver
Disease

Normal
Storage

-80℃

Pooled Human Liver S9 Fractions provide a fully characterized, relevant, reliable and reproducible in vitro tool.

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  • Human Liver S9 Fraction-200 Donors (0.5 mL)
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Home | Primary Cells | Subcellular Fractions | Human Liver S9 Fraction-200 Donors (0.5 mL)

Description

Human Liver S9 Fraction-200 Donors (0.5 mL) is a pooled subcellular preparation containing both microsomal and cytosolic enzymes, isolated from normal adult liver tissue. Derived from 200 individual donors, this high-diversity fraction offers a robust representation of population-wide metabolic capacity. It enables broad-spectrum xenobiotic metabolism studies. The S9 fraction supports early-stage compound screening, including metabolic stability assays, metabolite profiling, and drug interaction studies. With both oxidative and conjugative activities, it is particularly useful for modeling in vivo liver biotransformation in a single in vitro system. Each lot undergoes rigorous screening and isolation procedures and is tested to ensure it is free from contamination by HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Human Liver S9 Fraction 200 Donors 0.5 mL, Pooled Liver S9 200 Donors 0.5mL, Human Hepatic S9 Fraction 200, HLS9 200 Donors 0.5mL, Liver Post-Mitochondrial Supernatant 200 Pool
Species

Human
Cat.No

ABC-TC3676
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Liver S9 Fraction
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Liver
Disease

Normal
Storage

-80℃
Product Type

Subcellular Fractions

Application

  • This pooled S9 fraction enables comprehensive in vitro metabolism assessment, combining both microsomal and cytosolic pathways. It is widely used in metabolic stability assays, enzyme inhibition studies, and metabolite identification. Researchers use this preparation for screening CYP- and UGT-mediated clearance, assessing reactive metabolite formation, and evaluating phase II conjugation potential. The 200-donor pool enhances population relevance, making it a reliable tool for drug–drug interaction prediction, toxicity profiling, and compound ranking during early-stage drug discovery.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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