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Primary Cells

Human Mantle Cell Lymphoma Bone Marrow Mononuclear Cells (Relapsed/Refractory)

  • For research use only

Cat No.

ABC-TC3886
Product Type

Bone Marrow Mononuclear Cells
Cell Type

Mononuclear Cell
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Bone Marrow
Disease

Mantle Cell Lymphoma
Storage

Liquid Nitrogen

Human Mantle Cell Lymphoma Bone Marrow Mononuclear Cells (Relapsed/Refractory) enable hematologic cancer modeling and translational immunology studies.

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  • Human Mantle Cell Lymphoma Bone Marrow Mononuclear Cells (Relapsed/Refractory)
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Home | Primary Cells | Human Primary Cells | PBMCs | Human Mantle Cell Lymphoma Bone Marrow Mononuclear Cells (Relapsed/Refractory)

Description

Human mantle cell lymphoma bone marrow mononuclear cells (Relapsed/Refractory) are derived from the bone marrow of patients who have failed standard therapies, reflecting a highly resistant and progressive disease state. These cells typically exhibit small to medium-sized lymphocytes with irregular nuclei, and condensed chromatin. They exhibit dysregulated cell cycle progression, impaired apoptosis, and sustained survival signals, contributing to therapy resistance. Human Mantle Cell Lymphoma Bone Marrow Mononuclear Cells express pan-B-cell markers (such as CD19, CD20, CD22). The cells are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

Product Code

Human Mantle Cell Lymphoma Bone Marrow Mononuclear Cells (Relapsed/Refractory), MCL BM-MNCs (RR), Relapsed MCL Bone Marrow MNCs, Refractory Mantle Cell Lymphoma BM Cells
Species

Human
Cat.No

ABC-TC3886
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Mononuclear Cell
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Bone Marrow
Disease

Mantle Cell Lymphoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Bone Marrow Mononuclear Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Human Mantle Cell Lymphoma Bone Marrow Mononuclear Cells (Relapsed/Refractory) serve as a critical ex vivo model for studying disease progression, drug resistance mechanisms, and novel therapeutic strategies. These cells are widely used in preclinical research to evaluate the efficacy of targeted therapies, including Bruton’s tyrosine kinase (BTK) inhibitors, BCL-2 antagonists, and proteasome inhibitors.

Citation

When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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