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Primary Cells

Human Ovarian Fibroblasts

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    1

  • 152
Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They have been extensively used for a wide range of cellular and molecular studies. This is mainly because they are one of easiest types of cells to grow in culture, and their durability makes them amenable to a wide variety of manipulations ranging from studies employing […]
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Home | Primary Cells | Human Primary Cells | Reproductive System Primary Cells | Human Ovarian Fibroblasts
Product Code

HOF
Species

Human
Cat.No

ABC-TC3741
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Fibroblast
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Ovarian
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Female Reproductive Cells

Description

Human Ovarian Fibroblasts are isolated from healthy human ovaries and serve crucial functions in tissue maintenance. They are responsible for synthesizing components of the extracellular matrix, supporting the structural integrity of connective tissues, and actively participating in wound healing processes. In the presence of ovarian cancer cells, these fibroblasts within the stroma undergo significant structural and biochemical changes. Ovarian cancer cells prompt normal ovarian fibroblasts to release a diverse range of peptides, including growth factors, chemokines, collagens, and matrix-modifying enzymes, creating a pro-tumorigenic and anti-immunogenic microenvironment that facilitates cancer progression and metastasis.

 

Why choose Human Ovarian Fibroblasts from AcceGen?

Human Ovarian FibroblastsAcceGen’s Human Ovarian Fibroblasts are cryopreserved at passage one, with each vial containing over 500,000 viable cells in 1mL volume. They exhibit spindle morphology and are fibronectin-positive. The cells are free from HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi, ensuring their safety. Additionally, they can undergo up to 15 population doublings as per provided instructions, making them an ideal tool for research and experimentation.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

  • FOR RESEARCH USE ONLY

  • Human Ovarian Fibroblasts find valuable applications due to their stimulatory role in cancer development and invasive behavior. They serve as essential in vitro models for studying the pathophysiology of ovarian diseases, offering insights into disease mechanisms. Moreover, these fibroblasts prove to be indispensable tools for establishing in vitro disease models, enabling High Throughput and High Content Screening, thereby advancing research and potential therapeutic interventions.

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