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Human Pancreatic Epithelial Cells

Product Name

Human Pancreatic Epithelial Cells

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Cat.No

ABC-TC3744

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Human Pancreatic Epithelial Cells are isolated from healthy pancreatic tissue and constitute a vital component of the mature pancreas, which features an intricate, branching tubular epithelial network predominantly serving exocrine functions. As the pancreatic epithelium differentiates during late gestation, acinar cells mature at the branch tips, while ductal and endocrine progenitors emerge in the branch stalks. Through delamination, endocrine cells break away from their neighboring epithelial cells and come together to form islets. Simultaneously, the remaining tubular epithelium gives rise to ductal branches. This coordinated growth from a common pre-pancreatic epithelium results in the harmonious integration of both exocrine and endocrine compartments, forming a dual-function organ.

 

Why choose Human Pancreatic Epithelial Cells from AcceGen?

Human Pancreatic Epithelial Cells are cryopreserved at passage one, delivered frozen, and each vial contains over 500,000 viable cells. AcceGen guarantees their ability to undergo 15 population doublings when following the provided expansion instructions.

Disease

Normal

Source Organ

Pancreas

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

Human Pancreatic Epithelial Cells find valuable applications in scientific research, particularly in investigating the functional impact of activating point mutations in the K-Ras oncogene, which are prevalent in pancreatic cancer and play a crucial role in its early development. These cells serve as an in vitro model to study the transformation of normal pancreatic epithelial cells into cancerous ones. Additionally, they are utilized to identify potential human pancreatic carcinogens by subjecting them to various factors for exposure analysis.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Epithelial

Growth Mode

Adherent

Product Type

Pancreatic Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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