Rat Pancreatic Epithelial Cells

Description

Rat Pancreatic Epithelial Cells (RPECs) are specialized cells derived from the epithelial lining of the pancreas in rats. These cells are primarily categorized into ductal, acinar, and islet cells, each exhibiting distinct morphological features. They play a key role in exocrine pancreatic function, with ductal cells secreting bicarbonate-rich fluids to neutralize gastric acid and acinar cells producing digestive enzymes like amylase and lipase to aid nutrient breakdown, and their dysfunction is linked to pancreatitis and pancreatic cancer. Key molecular markers include epithelial markers such as ZO-1, E-cadherin, and CK18. To ensure the quality of these primary cells, repeated freeze-thaw cycles are not recommended due to the fragile nature of these cells. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.