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| Product Code | HSwC |
| Species | Human |
| Cat.No | ABC-TC3793 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Schwann Cell |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Peripheral Nerves |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Nervous Cells |
| Key Features | -Backed by AcceGen advanced technology |
Human Schwann Cells are derived from the peripheral nervous system. They are a type of glial cells and play an important role in supporting the development, function, and regeneration of peripheral nerves. These cells are able to secrete various growth factors to promote axonal growth, such as nerve growth factor, brain-derived neurotrophic factor, ciliary neurotrophic factor, neurotrophin-3, fibroblast growth factor and conserved dopamine neurotrophic factor. Schwann cells exhibit bipolar or tripolar morphology and grow in an adherent monolayer in vitro.Following nerve injury, Schwann cells undergo phenotypic changes to create a regenerative microenvironment by clearing myelin debris, forming regeneration tracks (Büngner bands), and upregulating growth factor production.They express characteristic markers such as S100β, p75^NTR, GFAP, and myelin protein zero (MPZ). Their plasticity and regenerative capacity make them promising candidates for cell-based therapies in peripheral nerve repair and neurodegenerative diseases.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
Human Schwann Cells obtained via in vitro culture are found useful for correcting the deficiencies of an injury or disease. Human Schwann Cell model system has great potential in therapeutic genes and drugs screening, treatment for acquired and inherited demyelinating neuropathies. These cells from specific patient could be used to study an onset to understand mechanisms.
