Human Sickle Cell Anemia PB Plasma

Description

Human Sickle Cell Anemia PB Plasma is derived from the peripheral blood of human donors diagnosed with sickle cell anemia, a genetic hemoglobinopathy. This plasma is separated from whole blood immediately after collection and cryopreserved. Functionally, it serves as a valuable tool for studying pathological processes in sickle cell anemia, such as vaso-occlusive crises, endothelial dysfunction, and organ damage. This plasma may contain increased levels of hemolysis- and inflammation-associated factors, such as cell-free hemoglobin, bilirubin, and pro-inflammatory cytokines (e.g., TNF-α, IL-6). Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.