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Human Skeletal Muscle Microvascular Endothelial Cells

Product Name

Human Skeletal Muscle Microvascular Endothelial Cells

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Cat.No

ABC-H0025Y

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Human skeletal muscle microvascular endothelial cells line the inner surface of microvascular capillaries within skeletal muscles. These cells serve as a critical barrier between circulating metabolites and tissues, playing a pivotal role in the regulation of nutrient exchange and immune cell migration. Muscle microvascular endothelial cells are characterized by their ability to uptake acetylated low-density lipoprotein (ac-LDL) and adenosine within the microvasculature, as well as their capacity to produce nitric oxide (NO).

Why choose Human Skeletal Muscle Microvascular Endothelial Cells from AcceGen?

Human skeletal muscle microvascular endothelial cells are isolated from human skeletal muscle tissue using AcceGen’s advanced techniques. Cells are cryopreserved to ensure the best viability. Each vial contains more than 5×10^5 cells in 1ml volume. Human skeletal muscle microvascular endothelial cells are quality tested with a cobblestone morphology and the expression of VE-cadherin and CD31/PECAM-1 by immunofluorescence.

Disease

Normal

Source Organ

Skeletal Muscle

Quality Control

All cell lots test negative for HIV-1, HBV, HCV, mycoplasma, yeast, fungi, and other pathogens.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

For research use only

Human primary skeletal muscle microvascular endothelial cells provide an ideal model for in vitro study of the biology and biochemistry of endothelial cells. They have been used in a wide range of research applications, including endothelial dysfunction, skeletal muscle regeneration, and interaction with other skeletal muscle cells such as satellite cells.

Key Features

– Backed by AcceGen advanced technology

– Cryopreserved for highest viability and plating efficiency

– Quality-guaranteed for accurate results

– Timely technical support for best experimental outcomes

 

Growth Conditions

37 ℃, 5% CO2

Cell Type

Endothelial

Growth Mode

Adherent

QuestionsthreeWhat are the primary research applications of HSkMECs?
Product Type

Skeletal Muscle Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial

Related Resources

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Frequently Asked Questions

  • What are Human Skeletal Muscle Microvascular Endothelial Cells (HSkMECs)?

    Human Skeletal Muscle Microvascular Endothelial Cells (HSkMECs) are specialized cells derived from the microvasculature of human skeletal muscle tissue. They are pivotal in studying vascular functions and pathologies within skeletal muscle.

  • What are the key characteristics of HSkMECs?

    HSkMECs exhibit properties such as the expression of endothelial markers (e.g., CD31, VE-cadherin), the ability to form capillary-like structures in vitro, and responsiveness to angiogenic factors.

  • What are the primary research applications of HSkMECs?

    HSkMECs are used in studies focusing on muscle regeneration, angiogenesis, diabetes-related vascular complications, and muscle perfusion. They are used in research to provide insight into the microvascular functions and pathologies associated with skeletal muscle. Researchers use HSkMECs to investigate the mechanisms by which high glucose levels and insulin resistance affect microvascular endothelial function, offering a model to study the vascular complications often seen in diabetic patients.

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