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Human Small Intestine Epithelial Cells | ||||
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Product Name | Human Small Intestine Epithelial Cells | |||
Price | Get Quote | |||
Cat.No | ABC-TC3814 | Species | Human | |
Size/Quantity | 1 vial | Biosafety Level | 1 | |
Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
Description | Lining on the intestinal lumen surface, human small intestinal epithelial cells (IECs) play a crucial role in food digestion, nutrient absorption and more importantly, constitutes a physical barrier that separates host from commensal microbiota. The crypts and villi border the surface area of intestinal epithelium and homes a variety of specialized epithelial lineages including absorptive enterocytes, enteroendocrine cells, goblet cells and Paneth cells. Unique to small intestine, Paneth cells lines in the base of crypts and secretes numerous antimicrobial peptides (AMPs) that strictly regulate antimicrobial resistance. Deregulated intestinal barrier function is often associated with increased risk of intestinal inflammation, systematic immune activation, development of inflammatory bowel disease (IBD) and increased sensitivity to chronic viral infections. | |||
Disease | Normal | |||
Source Organ | Intestine | |||
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. | |||
Recommended Medium And Supplement | ABM-TM3814 Human Small Intestine Epithelial Cells Medium Kit | |||
Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
Application | For research use only | |||
Key Features | – Backed by AcceGen advanced technology | |||
Growth Conditions | 37 ℃, 5% CO2 | |||
Cell Type | Epithelial | |||
Growth Mode | Adherent | |||
Product Type | Intestinal Cells | |||
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