Human Umbilical Cord Blood Mononuclear Cells

Description

Human Umbilical Cord Blood Mononuclear Cells (UCB-MNCs) are primary cells isolated from single-donor human umbilical cord blood, consisting of hematopoietic stem cells (CD34⁺), mesenchymal stem cells, lymphocytes, monocytes, and endothelial progenitor cells. They are derived from human umbilical cord blood, a rich source of pluripotent progenitors. These cells are round to slightly irregular in shape, non-adherent in culture, and cryopreserved immediately post-isolation without prior expansion. UCB-MNCs exhibit robust proliferation and multipotency under specific in vitro conditions, differentiating into osteoblasts, neurons, myocytes, and various immune lineages. They are highly utilized in hematopoiesis, immune modulation, tissue repair, and regenerative medicine. Flow cytometry using markers such as CD34, CD45, and CD14 allows phenotypic characterization and subpopulation analysis. UCB-MNCs cannot be passaged in vitro and should be handled carefully to avoid viability loss from freeze-thaw cycles.