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Human Villous Trophoblasts

Product Name

Human Villous Trophoblasts

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Cat.No

ABC-TC3870

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Human villous trophoblasts, isolated from placental villi, originate at the outer layer of the early blastocyst, serving as the vital conduit for nourishment exchange between the maternal endometrium and the developing embryo. These trophoblasts envelop the chorionic villi, enabling the exchange of gases and nutrients crucial for fetal development. Their initial adhesion to the uterine wall is a pivotal step in implantation and placental formation. Extravillous trophoblasts delve deep into the uterine wall, anchoring chorionic villi, and play a direct role in this attachment process. Villous trophoblasts are also responsible for synthesizing and releasing important hormones such as chorionic gonadotropin, placental lactogen, and angiogenin, while expressing genes like CXCR4, CCR5, and the prolactin gene family. During differentiation at villous-anchoring sites, they acquire CCR1 expression.

 

Why choose Human Villous Trophoblasts from AcceGen?

AcceGen’s Human Villous Trophoblasts are cryopreserved at passage one, delivered frozen, and each vial contains more than 1 million viable cells. These trophoblasts are characterized by HCG ELISA, ensuring their authenticity and functionality. They are rigorously screened and confirmed to be negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi, ensuring their safety for research applications.

Disease

Normal

Source Organ

Villous

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

Human villous trophoblasts offer versatile applications in scientific research. They serve as an ideal genetic platform for investigating cell differentiation and organogenesis while also enabling the development of disease models for high-throughput and high-content screening. These cells are invaluable for cell biologists studying the molecular mechanisms underlying human placental development and pathology, shedding light on key events in placental morphogenesis and growth, and enhancing our understanding of trophoblast activity regulation within the villous environment.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Trophoblast

Growth Mode

Adherent

Product Type

Female Reproductive Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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