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Immortalized Cell Lines

Immortalized Mouse Hepatic Sinusoidal Endothelial Cell Line – SV40

  • For research use only

Cat No.

ABI-TC189D
Product Type

Immortalized Cell Line
Cell Type

Endothelial
Species

Mouse
Growth Conditions

37 ℃, 5% CO2
Source Organ

Liver
Disease

Normal
Storage

Liquid Nitrogen

Immortalized Mouse Hepatic Sinusoidal Endothelial Cell Line – SV40 maintains HSEC features like vWF and caveolin-1, supporting liver vasculature studies.

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  • Immortalized Mouse Hepatic Sinusoidal Endothelial Cell Line – SV40
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Home | Immortalized Cell Lines | Immortalized Mouse Hepatic Sinusoidal Endothelial Cell Line – SV40

Description

Hepatic sinusoidal endothelial cells (HSECs) are an unique sub-population of liver that lines the hepatic sinusoids. Their role involves in clearing waste products from the blood, regulating pericyte contractility and innate immune functions. The Immortalised Mouse Hepatic Sinusoidal Endothelial Cells- SV40 is derived from C57BL/6 mouse HSECs that have maintained endothelial characteristics and HSEC-specific features such as vWF and caveolin-1. These cells also migrate in response to angiogenici growth factors, form vascular tube-like structures, endycytose acetylated low-density lipoprotein (AcLDL) and secrete proteins involved in matrix remodelling. In addition, these cells are easily transduced by retrovirus. The Immortalised Mouse Hepatic Sinusoidal Endothelial Cells- SV40 is therefore suitable for studying liver endothelial cell biology, including motility and angiogenesis.

Species

Mouse
Cat.No

ABI-TC189D
Quality Control

1. Real Time PCR was used to quantify SV40 gene expression in immortalized cell line. 2. Western blot was used to confirm the presence of endothelial markers such as vWF and caveolin-1.
Product Category Immortalized Cell Lines
Size/Quantity

1 vial
Cell Type

Endothelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Liver
Disease

Normal
Biosafety Level

2
Storage

Liquid Nitrogen
Product Type

Immortalized Cell Line
Immortalization Method

Serial passaging and transduction with pantropic recombinant retroviruses carrying SV40 Large T antigen
Morphology

Cobble-stone

Application

  • For research use only

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
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