For research use only
| Cat No. | ABC-TC0472 |
| Product Type | Human Liver Cancer Cell Lines |
| Cell Type | Epithelial-like |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Liver |
| Disease | Hepatocellular Cancer |
| Product Code | Jhh-4; JHH4 |
JHH-4,Human hepatocellular carcinoma cell line producing alpha-fetoprotein and albumin,used for liver cancer research, drug testing and functional studies.
JHH‑4 is a human hepatocellular carcinoma cell line established from a resected liver tumor of a 51‑year‑old male Japanese patient with hepatocellular carcinoma, exhibiting polygonal epithelial‑like morphology and adherent growth typical of liver cancer cells. This line synthesizes and secretes alpha‑fetoprotein (AFP) and albumin in vitro, reflecting hepatogenic and differentiated hepatocyte functions retained by the tumor cells. JHH‑4 has been characterized cytogenetically with modal chromosome numbers in aneuploid ranges consistent with malignant hepatocellular carcinoma and has been shown to be transplantable in nude mice, indicating tumorigenicity. These features support its use as a representative hepatocellular carcinoma model. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV‑1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | Jhh-4; JHH4 |
| Species | Human |
| Cat.No | ABC-TC0472 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial-like |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Liver |
| Disease | Hepatocellular Cancer |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Liver Cancer Cell Lines |
JHH‑4 is used as an in vitro human hepatocellular carcinoma model for studies of liver cancer biology, including investigations of AFP and albumin expression patterns, tumor cell proliferation, and genotypic/phenotypic characteristics of HCC. It is also applied in screening and evaluation of anticancer agents targeting hepatocellular carcinoma pathways and mechanisms.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
Kassab M. Identification and molecular characterization of arginine deiminase-producing bacteria in Egyptian soil from various soil environments. Journal of Medical and Life Science. 2023;5(1):43-75. doi:10.21608/jmals.2023.295732
