For research use only
| Cat No. | ABC-TC0688 |
| Product Type | Human Gastric Cancer Cell Lines |
| Cell Type | Epithelial-like |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Stomach |
| Product Code | MKN7; MKN 7 |
Delve into the MKN-7 cell line, isolated from a gastric cancer patient. Understand its adherent culture properties and significance in cancer research.
MKN7 is a human gastric adenocarcinoma cell line established from a moderately differentiated tubular adenocarcinoma of the stomach in a 39-year-old Japanese male. These adherent cells exhibit polygonal, epithelial-like morphology and show intestinal differentiation features, including cell polarity and microvilli with core filaments, relevant to absorptive and secretory functions in vitro and in nude mouse models. MKN7 cells express epithelial markers such as cytokeratins and gastric-specific proteins, reflecting their gastric epithelial origin. They harbor genetic alterations commonly observed in gastric cancer, including mutations in oncogenes and tumor suppressors like TP53. With moderate proliferative capacity, MKN7 cells are widely used to study gastric cancer biology, tumor progression, and chemotherapeutic responses, making them valuable for investigating molecular mechanisms and therapeutic screening in gastric carcinoma research.
| Product Code | MKN7; MKN 7 |
| Species | Human |
| Cat.No | ABC-TC0688 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial-like |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Stomach |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Gastric Cancer Cell Lines |
The MKN-7 gastric cancer cell line is a valuable model for investigating the molecular characteristics of gastric carcinoma. Its distinct biological properties support studies on tumor progression and aid in the development of targeted therapeutic strategies for gastrointestinal cancers.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
