For research use only
| Cat No. | ABC-TC0401 |
| Product Type | Human Bone Cancer Cell Lines |
| Cell Type | Epithelial-like |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Bone |
| Disease | Osteosarcoma |
| Product Code | MNNG/HOS; MNNG-HOS; HOS-MNNG; HOS/MNNG; MNNGHOS; MNNG-HOS (Cl#5); MNNG/HOS Clone F-5; MNNG; R-1059-D; TE85; Te85; TE-85; HOS-TE85; Hos TE-85; HOS TE 85; HOS TE85; HOS (TE85); HOS(TE85); HOS (TE85, Clone F5); MNNG-HOS (TE 85, clone F-5); TE-85 clone F-5; H |
MNNG/HOS Cl #5 osteosarcoma cells enable cancer research, transformation studies and tumor biology analysis with sensitivity to chemical and viral factors.
MNNG/HOS Cl #5 is a human osteosarcoma cell line derived via multiple cloning of the parental HOS line treated with N-methyl-N′-nitro-N-nitrosoguanidine (MNNG). These cells exhibit epithelial-mesenchymal transition (EMT) morphology, adhere in monolayers, and exhibit high clonogenic potential. They are hypertriploid with complex karyotypes typical of transformed osteoblasts. MNNG/HOS Cl #5 cell line is tumorigenic and metastatic in immunodeficient mice, producing bone-like tumors and lung metastases. It is widely used as a model to study bone cancer progression, metastasis biology, chemotherapeutic sensitivity, and signaling pathways related to osteosarcoma. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | MNNG/HOS; MNNG-HOS; HOS-MNNG; HOS/MNNG; MNNGHOS; MNNG-HOS (Cl#5); MNNG/HOS Clone F-5; MNNG; R-1059-D; TE85; Te85; TE-85; HOS-TE85; Hos TE-85; HOS TE 85; HOS TE85; HOS (TE85); HOS(TE85); HOS (TE85, Clone F5); MNNG-HOS (TE 85, clone F-5); TE-85 clone F-5; H |
| Species | Human |
| Cat.No | ABC-TC0401 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial-like |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Bone |
| Disease | Osteosarcoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Bone Cancer Cell Lines |
MNNG/HOS Cl #5 cells are used in modeling bone cancer progression, metastasis, and invasion. Their high clonogenic and tumorigenic potential makes them suitable for in vitro assays of cell migration, chemotherapeutic resistance, and signaling pathways associated with bone tumor malignancy and metastasis. These cells also provide valuable insights into the molecular mechanisms driving osteosarcoma’s aggressive behavior, aiding in the identification of potential therapeutic targets.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
