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Primary Cells

Mouse Aorta Fibroblasts

  • For research use only

Cat No.

ABC-TC3912
Product Type

Mouse Primary Cells
Cell Type

Fibroblast
Species

Mouse
Growth Conditions

37 ℃, 5% CO2
Source Organ

Aorta
Disease

Normal
Storage

Liquid Nitrogen

Mouse aorta fibroblasts, 2-week ICR mouse.

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  • Mouse Aorta Fibroblasts
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Home | Primary Cells | Animal Primary Cells | Mouse Primary cells | Mouse Aorta Fibroblasts

Description

Mouse Aorta Fibroblasts (MAFs) are isolated from the aortic tissue of healthy mice. As a type of connective tissue cell, fibroblasts play a crucial role in maintaining tissue integrity, extracellular matrix (ECM) synthesis, and wound healing. These cells exhibit typical spindle-shaped morphology and adhere to the culture surface during growth. Functionally, MAFs participate in ECM remodeling, contributing to vascular homeostasis. Dysregulation of these cells has been associated with vascular diseases such as atherosclerosis. The cells express vimentin. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

Mouse Aorta Fibroblasts, Mouse Aortic Fibroblasts, Aorta Stromal Cells (Mouse), Murine Aortic Fibroblasts
Species

Mouse
Cat.No

ABC-TC3912
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Fibroblast
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Aorta
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Mouse Primary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Mouse Aorta Fibroblasts can serve as an in vitro cell model to investigate vascular remodeling, fibrotic diseases, and fibroblast-immune interactions, particularly in atherosclerosis and aortic aneurysms. For instance, by studying their secretion of extracellular matrix proteins and response to inflammatory cytokines, researchers can better understand the molecular mechanisms underlying vascular fibrosis and smooth muscle cell dysfunction. This supports discovery research and target identification related to cardiovascular conditions associated with altered fibroblast activity.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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