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| Product Code | OSC19; Osc19 |
| Species | Human |
| Cat.No | ABC-TC0877 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Tongue |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Tongue Cancer Cell Lines |
OSC-19 is a human squamous cell cancer cell line that was originally isolated from the tongue tissue of a 61-year-old East Asian male patient with tongue squamous cell carcinoma. OSC-19 exhibits epithelial-like morphology and adherent culture properties. The characteristic of cultured OSC-19 is lower proliferating activity, lower secretion of laminin, and higher secretion of fibronectin. In addition, OSC-19 is sensitive to EGF treatment. A study utilized a xenotransplantation model to investigate the metastasis mechanism of oral cancer; this work confirmed that OSC-19 is tumorigenic and causes lymph node metastasis.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
OSC-19 holds diverse applications in research, serving as an in vitro invasion model to dissect the drivers of invasive behavior. It can be utilized for exploring malignant transformation mechanisms, assessing cytotoxic impacts of compounds on human tongue squamous carcinoma, and dissecting relevant pathways. Moreover, OSC-19 aids in identifying pivotal factors in oral cancer invasion and metastasis, paving the way for novel therapies like siRNA-based approaches, ultimately contributing to advancements in this field.
