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Tumor Cell Lines

PC-9

  • For research use only

Cat No.

ABC-TC0907

Product Type

Human Lung Cancer Cell Lines

Species

Human

Growth Conditions

37 ℃, 5% CO2

Product Code

PC9; PC-9/S1; PC-9S1

PC-9 cells carry EGFR exon 19 deletion and are used in NSCLC modeling, drug sensitivity testing, and targeted therapy evaluation in lung cancer studies.

Product Image

Description

PC-9
The PC-9 cell line is a human non-small cell lung cancer (NSCLC) cell line derived from lung adenocarcinoma. It exhibits a mixture of round and spindle-shaped cells. PC-9 cells display both adherent and suspension growth. PC-9 cells carry a deletion mutation in exon 19 of the EGFR gene and are highly sensitive to EGFR-TKI gefitinib. They are an important model for studying the mechanism of drug resistance in targeted therapy of non-small cell lung cancer (NSCLC). Its derived cell lines such as PC-9/ZD and PC-9/GR can simulate clinical drug resistance and be used to explore drug resistance gene regulatory networks and combination drug strategies.
Product Code

PC9; PC-9/S1; PC-9S1

Species

Human

Cat.No

ABC-TC0907

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Human Lung Cancer Cell Lines

Application

  • PC-9 cells are widely used in cancer research. They can be used to investigate the impact of α-tocopherol on cytotoxic drugs, investigating whether it enhances or diminishes their effectiveness against NSCLC. Additionally, PC-9 cells serve as a model to study resistance to tyrosine kinase inhibitors (TKIs) in lung cancer, helping understand the mechanisms involved. Moreover, they can be utilized in tumorigenicity studies to assess the tumorigenic potential and characteristics of NSCLC. These applications contribute to advancing our understanding of NSCLC biology, drug resistance, and the development of effective treatment strategies.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Inquiring PC-9

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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