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Calu-6

Product Name

Calu-6

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Product Code

CaLu-6; CALU-6; Calu.6; Calu 6; Calu6; CALU6; CaLu-06

Cat.No

ABC-TC0112

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Calu-6 is a human lung adenocarcinoma cell line that originated from lung metastasis in lung adenocarcinoma in 1971. It exhibits epithelial morphology and has the ability to express human renin mRNA with significant increases in its steady-state levels in response to cAMP analogues and adenylyl cyclase activators. Notably, Calu-6 carries a defect in the Fanconi Anemia (FA)-BRCA pathway, which plays a vital role in tumor suppression. The growth of Calu-6 cells can be effectively hindered by Pyrogallol (PG) or Antimycin A (AMA), providing potential avenues for inhibiting their proliferation.

 

Why choose Calu-6 from AcceGen?

The Calu-6 cell from AcceGen exhibits several notable features. It boasts high viability, ensuring the robustness and longevity of experimental studies. It is characterized by sterility, being rigorously tested and confirmed negative for mycoplasma contamination, ensuring reliable and uncontaminated cell cultures. The cells are identified through Short Tandem Repeat analysis, ensuring their authenticity and consistency. The cells are incubated under optimal conditions, benefiting from the expertise of professional operators, who ensure precise and controlled growth environments for consistent and reproducible experimental outcomes.

Disease

Lung Adenocarinoma

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

The Calu-6 cell line is utilized as a model to investigate tumor suppression factors and pathways for potential therapies. It has been instrumental in studying the antiproliferative mechanism of apoptosis and understanding the molecular mechanisms of cytotoxic drugs used in lung cancer treatment. Additionally, Calu-6 contributes to the development of novel agents that target specific intracellular pathways associated with cancer cell properties, aiding the ongoing efforts in developing effective treatments for lung cancer and other types of cancer.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Epithelial

Growth Mode

Adherent

Product Type

Human Lung Cancer Cell Lines

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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