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PC-9 | ||||
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Product Name | PC-9 | |||
Price | Get Quote | |||
Product Code | PC9; PC-9/S1; PC-9S1 | |||
Cat.No | ABC-TC0907 | Species | Human | |
Size/Quantity | 1 vial | Biosafety Level | 1 | |
Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
Description | PC-9, previously known as PC-14, is a human non-small cell lung cancer (NSCLC) cell line, which has a deletion mutation in exon 19 of the EGFR gene. It was derived from an undifferentiated human adenocarcinoma of lung tissue, consisting of a heterogeneous mixture of round and spindle-shaped cells. PC-9 cells demonstrate both adherent and suspension growth characteristics. They can be cultured in either DMEM supplemented with 10% fetal bovine serum(FBS) or RPMI 1640 with 2mM Glutamine and 10% FBS under 5% CO2 at 37 °C. 0.25% trypsin or trypsin/EDTA is recommended for the removal of attached cells. For seeding PC-9 cells, a density of 2-4×10,000 cells/cm2 is suggested, and a 1:8 split ratio is recommended for subculturing.
Why choose PC-9 from AcceGen? | |||
Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
Application | FOR RESEARCH USE ONLY PC-9 cells, a human non-small cell lung cancer (NSCLC) cell line, have multiple applications in cancer research. They are used to study the effects of α-tocopherol on cytotoxic drugs, investigating whether it enhances or diminishes their effectiveness against NSCLC. Additionally, PC-9 cells serve as a model to study resistance to tyrosine kinase inhibitors (TKIs) in lung cancer, helping understand the mechanisms involved. Moreover, they are used in tumorigenicity studies to evaluate the tumor-forming potential and behavior of NSCLC. These applications contribute to advancing our understanding of NSCLC biology, drug resistance, and the development of effective treatment strategies. | |||
Growth Conditions | 37 ℃, 5% CO2 | |||
Product Type | Human Lung Cancer Cell Lines | |||
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