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| Product Code | PLC PRF 5; PLC/PRF5; PLCPRF5; PLC-8024; PLC8024; PLC |
| Species | Human |
| Cat.No | ABC-TC0914 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Liver |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Liver Cancer Cell Lines |
PLC-PRF-5 is a carcinoma cell line derived from a hepatoma donor’s liver. Although it synthesizes hepatitis B surface antigen (HBSAg), it does not demonstrate the capability to produce infectious Hepatitis B virus. This cell line expresses various oncogenes, including c-abl, c-fes, c-fms, c-myc, c-ha-ras, and c-sis. In culture, these cells exhibit hepatocyte-like characteristics, with a doubling time of approximately 35-40 hours and a plating efficiency of 40-50%. Additionally, PLC-PRF-5 cells display a heteroploid chromosome pattern with an average of 56 chromosomes.
Why choose PLC-PRF-5 from AcceGen?
PLC-PRF-5 cell line boasts high viability and quality, ensuring robust experimental outcomes when incubated under optimal conditions. It is maintained in a sterile environment, regularly monitored for mycoplasma, bacterial, and fungal contamination to guarantee purity. The cell line’s identity is confirmed through STR analysis, making it a reliable and well-maintained resource for research purposes.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
PLC-PRF-5 cell line offers a versatile platform for various research applications. In the realm of cancer research, it serves as a valuable tool for studying hepatocellular carcinoma, shedding light on the critical factors driving its malignant progression. Furthermore, its ability to produce hepatitis B surface antigen (HBSAg) makes it relevant in infectious disease research, particularly in understanding the mechanisms behind hepatitis B infection. Additionally, PLC-PRF-5 contributes to sexually transmitted disease research, potentially providing insights into liver-related complications of certain sexually transmitted infectionsp. Moreover, this cell line supports investigations aimed at identifying prognostic indicators for patients with liver cancer, offering significant potential in advancing our understanding of this challenging disease.
