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Rat Aortic Endothelial Cells | ||||
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| Product Name | Rat Aortic Endothelial Cells | |||
| Price | Get Quote | |||
| Cat.No | ABC-TC4069 | Species | Rat | |
| Size/Quantity | 1 vial | Biosafety Level | 1 | |
| Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
| Description |
Why choose Rat Aortic Endothelial Cells from AcceGen? Rat Aortic Endothelial Cells from AcceGen are of exceptionally high quality, isolated from adult rat aorta and cryopreserved at the early passage, with each vial containing over 0.5×106 cells. Each lot undergoes rigorous testing for proper morphology, population doublings, and is confirmed to be free from HIV, Hepatitis B, Hepatitis C, mycoplasma, bacteria, and fungi. These cells are capable of being cultured up to at least the 6th passage, making them a reliable and durable resource for research applications. | |||
| Disease | Normal | |||
| Source Organ | Aortic | |||
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. | |||
| Recommended Medium And Supplement | ABM-TM4069 Rat Aortic Endothelial Cells Medium Kit | |||
| Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
| Application | FOR RESEARCH USE ONLY Rat Aortic Endothelial Cells (RAEC) offer a versatile and indispensable model system for investigating various facets of cardiovascular function and disease. They play a crucial role in research related to the immune system, graft rejection, and the development of 3D endothelialized engineered tissues. Moreover, RAEC are instrumental in drug discovery efforts and compatibility testing for stent-grafts, making them a pivotal tool in advancing our understanding of cardiovascular health and enabling medical advancements in the field. | |||
| Growth Conditions | 37 ℃, 5% CO2 | |||
| Cell Type | Endothelial | |||
| Growth Mode | Adherent | |||
| Product Type | Rat Primary Cells | |||
| Product Image |  | |||
Rat Aortic Endothelial Cells (RAEC), isolated from the rat aorta, are a pivotal component of the blood-tissue interface. They exhibit a dichotomous functionality, generating both antithrombotic factors such as tissue-type plasminogen activator (t-PA) and prothrombotic elements like plasminogen activator inhibitor-1 (PAI-1). Upon stimulation by tumor necrosis factor-alpha (TNFalpha), RAEC undergo alterations in growth characteristics and release cytokines, notably granulocyte-macrophage colony-stimulating factor (GM-CSF). Moreover, RAEC exhibit reduced permeability in response to Intermedin (IMD) due to the enhanced accumulation of VE-cadherin at their intercellular junctions. Consequently, these cells serve as an invaluable model for investigating vascular physiology and the intricate regulation of blood-tissue interactions.- ONLINE INQUIRY
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