Rat Brain Glial Cells

Description

Rat Brain Glial Cells are primary cells isolated from the cerebral cortex of rats. These glial cells represent a mixed population, including astrocytes, oligodendrocyte progenitor cells (OPCs), and microglia. Harvested under sterile conditions, the cells are cryopreserved at an early passage to maintain native morphology and biological integrity. Morphologically, astrocytes present a polygonal or stellate appearance, while microglia exhibit a branched form in vitro. Functionally, glial cells regulate synaptic signaling, maintain the blood-brain barrier (BBB) function, modulate neuroinflammation, and provide metabolic support to neurons. Studies have implicated glial dysfunction in various neurodegenerative and inflammatory diseases, including Alzheimer's disease, multiple sclerosis, and glioma. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.