Primary Cells

Rat brain microvascular endothelial cells

  • For research use only

Cat No.

ABC-TC4096

Product Type

Rat Primary Cells

Cell Type

Endothelial

Species

Rat

Growth Conditions

37 ℃, 5% CO2

Source Organ

Brain

Disease

Normal

Storage

Liquid Nitrogen

Rat brain microvascular endothelial cells, Primary brain endothelial cells from 1-day-old Sprague-Dawley rats for vascular and BBB research studies.

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Description

Rat Brain Microvascular Endothelial Cells (RBMVECs) are primary endothelial cells isolated from the cerebral microvasculature of healthy rats. These cells line the inner surface of brain capillaries and are collected under sterile conditions before being cryopreserved at an early passage to maintain their native phenotype. RBMVECs exhibit a typical cobblestone morphology and grow as adherent monolayers. Functionally, they form the basis of the blood–brain barrier (BBB), contributing to selective permeability, tight junction formation, and neurovascular signaling. These cells express endothelial-specific marker CD31. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Rat Brain Microvascular Endothelial Cells, Rat BMECs, Brain MVECs, BMECs

Species

Rat

Cat.No

ABC-TC4096

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Endothelial

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Brain

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Rat Primary Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • RBMVECs serve as a robust in vitro model for investigating blood–brain barrier physiology, neuroinflammation, CNS drug delivery, and neurodegenerative diseases. These cells are widely used in studies of cerebral ischemia (hypoxia responses), Alzheimer’s disease (amyloid-beta transport), and multiple sclerosis (leukocyte transmigration). Their high physiological relevance makes them ideal for drug permeability screening, nanoparticle transport studies, and neurovascular coupling research.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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