Rat Lung Fibroblasts

Description

Rat Lung Fibroblasts (RLF) are primary mesenchymal cells isolated from the interstitial tissue of healthy rat lungs. These cells display a characteristic spindle-like morphology and adhere strongly to standard tissue culture-treated plastic surfaces, forming a monolayer under standard conditions. They play a vital role in maintaining lung structure, extracellular matrix (ECM) turnover, and responding to injury or inflammation. Rat Lung Fibroblasts express mesenchymal markers including vimentin, fibronectin, and platelet-derived growth factor receptor-α (PDGFR-α). Cells are cryopreserved at early passage to retain high post-thaw viability, stable proliferation, and consistent phenotype. For best results and long-term functionality, repeated freeze-thaw cycles should be avoided. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.