For research use only
| Cat No. | ABC-TC4165 |
| Product Type | Rat Primary Cells |
| Cell Type | Macrophage |
| Species | Rat |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Macrophages are cells produced by the differentiation of monocytes in tissues.
Rat Macrophages are non-proliferative, terminally differentiated primary immune cells derived from myeloid progenitor cells in the bone marrow, which differentiate into monocytes in the circulation before migrating into tissues and maturing into macrophages. Rat macrophages are large, irregularly shaped cells with abundant cytoplasm. They display phagocytic capabilities and often contain vacuoles or lysosomal granules due to their role in engulfing pathogens and cellular debris. These cells are a key component of the innate immune system and exhibit remarkable plasticity, adapting their phenotype in response to microenvironmental cues. They participate in phagocytosis, antigen presentation, cytokine secretion, and tissue remodeling. Key markers for rat macrophages include surface receptors such as CD11b and CD68. To ensure the quality of these primary cells, repeated freeze-thaw cycles are not recommended due to the fragile nature of these cells. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | Rat Macrophage, Rat Macrophages, Macrophages, MΦ |
| Species | Rat |
| Cat.No | ABC-TC4165 |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Macrophage |
| Growth Mode | Suspension |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Rat Primary Cells |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Rat macrophages are widely utilized in biomedical research due to their critical roles in immunity, inflammation, and tissue homeostasis. These primary rat macrophages serve as key models for studying phagocytosis, cytokine responses, and oxidative stress, helping assess drug safety and immunomodulatory effects. Additionally, rat macrophages are essential in cancer research.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
