Rat Mammary Microvascular Endothelial Cells

Description

Rat Mammary Microvascular Endothelial Cells (RMMECs) are primary endothelial cells isolated from mammary tissue of adult Sprague-Dawley rats. These cells exhibit a typical cobblestone-like morphology and grow as adherent monolayers with tight cell-cell junctions. These cells regulate blood flow, mediate inflammatory responses, and support mammary gland development and lactation by facilitating selective transport of hormones and nutrients, playing a critical role in vascular homeostasis, nutrient exchange, and immune cell trafficking. RMMECs express endothelial cell markers including CD31. To ensure the quality of these primary cells, repeated freeze-thaw cycles are not recommended due to the fragile nature of these cells. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.