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Primary Cells

Rat Neurons-Dorsal Spinal Cord

  • For research use only

Cat No.

ABC-TC4177

Product Type

Rat Primary Cells

Cell Type

Neuron

Species

Rat

Growth Conditions

37 ℃, 5% CO2

Source Organ

Brain

Disease

Normal

Storage

Liquid Nitrogen

The tissue of the central nervous system is made up of two classes of cells that may be broadly categorized as neurons and glia.

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Description

Rat Neurons-Dorsal Spinal Cord are primarily derived from the spinal cord and are predominantly sensory relay neurons and interneurons located in the dorsal horn. Rat Neurons-Dorsal Spinal Cord exhibit a highly arborized neurite network when cultured, forming complex synaptic connections critical for sensory signal integration. They modulate central sensory pathways through glutamatergic and peptidergic neurotransmission, and process nociceptive, proprioceptive, and mechanosensory inputs from peripheral dorsal root ganglia . These cells are terminally differentiated and non-proliferative in vitro. They express neuronal markers such as β-tubulin III and MAP2. To ensure the quality of these primary cells, repeated freeze-thaw cycles are not recommended due to the fragile nature of these cells. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

Rat Neurons-Dorsal Spinal Cord, Rat Dorsal Spinal Neurons, Dorsal Spinal Neurons

Species

Rat

Cat.No

ABC-TC4177

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Neuron

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Brain

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Rat Primary Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Rat dorsal spinal cord neurons are widely utilized in vitro models to study sensory processing, neuropathic pain mechanisms, and spinal circuit plasticity. Their ability to form functional synapses with dorsal root ganglion (DRG) neurons makes them valuable for co-culture systems investigating nociceptive signaling, particularly in response to inflammatory mediators or pH shifts.

Citation

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