For research use only
| Cat No. | ABC-TC4192 |
| Product Type | Rat Primary Cells |
| Cell Type | Macrophage |
| Species | Rat |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Rat peritoneal macrophages (RPMAC) are derived from the peritoneal cavity of Sprague–Dawley rats.
Rat Peritoneal Macrophages are primary immune cells derived from the peritoneal cavity of rats. These cells belong to the mononuclear phagocyte system and play a crucial role in innate immunity. Morphologically, they exhibit a rounded or slightly irregular shape in suspension. Activated macrophages may adopt an elongated or spindle-shaped appearance. Peritoneal macrophages are involved in phagocytosis, antigen presentation, and cytokine secretion, modulating inflammation and tissue homeostasis. They contribute to pathogen clearance, wound healing, and immune surveillance. Key surface markers include CD11b and CD68. To ensure the quality of these primary cells, repeated freeze-thaw cycles are not recommended due to the fragile nature of these cells. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | RPMAC |
| Species | Rat |
| Cat.No | ABC-TC4192 |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Macrophage |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Rat Primary Cells |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Rat Peritoneal Macrophages (fresh cells in suspension) are widely used in biomedical research due to their accessibility, functional plasticity, and relevance to human immune responses. These cells serve as a primary model for studying innate immunity, phagocytosis, and inflammatory responses. In toxicology, they are employed to assess the immunomodulatory effects of drugs, nanoparticles, and environmental pollutants by measuring cytokine secretion, oxidative stress, and phagocytic activity.
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