Rat Pulmonary Vein Endothelial Cells

Description

Rat Pulmonary Vein Endothelial Cells (RPVECs) are specialized endothelial cells lining the pulmonary veins that return oxygenated blood from the lungs to the left atrium. These cells originate from the mesodermal lineage and exhibit a typical endothelial morphology, characterized by a cobblestone-like appearance when confluent and a spindle-shaped structure when migrating or proliferating. RPVECs play essential roles in maintaining vascular barrier integrity, regulating blood flow, and mediating inflammatory responses through the secretion of cytokines and adhesion molecules. RPVECs highly express the endothelial cell marker CD31. To ensure the quality of these primary cells, repeated freeze-thaw cycles are not recommended due to the fragile nature of these cells. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.