v6.5 Mouse Embryonic Stem (ES) Cells

Description

v6.5 Mouse Embryonic Stem Cells are derived from the Inner Cell Mass (ICM) of the blastocyst stage. These mouse ES cells (V6.5), also referred to as mESCs, exemplify the properties of mouse stem cells. They provide a model to study pluripotency, self-renewal, and differentiation potential. They possess developmental pluripotency and self-renewal capability. Morphologically, mESCs exhibit typical undifferentiated characteristics, featuring large nuclei with prominent nucleoli, relatively scant cytoplasm, and abundant euchromatin. mESCs express pluripotency marker genes, such as Oct4, Nanog, and Sox2, as well as the surface antigen SSEA-1 (murine-specific). Functionally, mESCs can be directed to differentiate into various cell types of the three germ layers (ectoderm, mesoderm, and endoderm), including neurons, cardiomyocytes, and hematopoietic cells. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.