For research use only
| Cat No. | ABC-TC0048 |
| Product Type | Rat Liver Cancer Cell Lines |
| Cell Type | Epithelial |
| Species | Rattus Norvegicus |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Liver |
| Disease | Hepatoma |
| Product Code | ARL 6; Adult Rat Liver-6 |
Rat Wistar liver hepatoma. Derived from the liver of a Wistar rat. Useful in quantitative carcinogenesis studies.
ARL-6 is an epithelial tumor cell line derived from liver tissue of an adult Wistar rat diagnosed with hepatoma. It exhibits polygonal morphology with adherent monolayer growth under standard culture conditions. This line was developed for use in chemical carcinogenesis models and demonstrates stable proliferative behavior in vitro. ARL-6 cells are tumorigenic in vivo, with newborn Wistar rats offering higher sensitivity for detecting tumorigenicity than nude mice, likely due to syngeneic compatibility and developmental permissiveness. Cytogenetic analyses reveal chromosomal alterations associated with rat hepatocellular carcinoma, including aneuploidy and structural aberrations. ARL-6 is a valuable tool for liver cancer research, enabling reproducible studies on tumor initiation, progression, and response to carcinogens. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | ARL 6; Adult Rat Liver-6 |
| Species | Rattus Norvegicus |
| Cat.No | ABC-TC0048 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Liver |
| Disease | Hepatoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Rat Liver Cancer Cell Lines |
ARL-6 cell line is extensively used in experimental hepatocarcinogenesis and chemical toxicity studies. Its derivation from Wistar rat liver tumor tissue makes it highly relevant for modeling liver-specific neoplasia and for evaluating dose-dependent carcinogen responses. Researchers employ ARL-6 in both in vitro assays and in vivo transplantation models to assess tumor growth kinetics, differentiation states, and oncogene activation. The cell line’s strong compatibility with newborn rat models supports sensitive tumorigenicity testing, outperforming nude mice in certain detection settings. ARL-6 is also used in gene expression profiling, chemoprevention trials, and hepatic metabolism research to study mechanisms of liver tumor development and therapeutic intervention.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
