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| Product Code | Bt-474; BT474 |
| Species | Human |
| Cat.No | ABC-TC0085 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Breast |
| Disease | Ductal Cancer |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Breast Cancer Cell Lines |
BT-474 is a human breast tumor cell line that was originally isolated from the breast tissue of a 60-year-old white female patient with invasive ductal carcinoma. BT-474 exhibits epithelial-like morphology and adherent/patchy culture properties. BT-474 is shown as aneuploid expression with the chromosome mode numbers of 55. These cells express high levels of progesterone receptors (PR), estrogen receptor positive (ER), and human epidermal growth factor receptor 2 (HER2). BT-474 is tumorigenic in nude mice. These characteristics make it a powerful model for studying hormone-responsive breast cancer.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
The BT-474 cell line finds valuable applications in preclinical breast cancer research, offering a direct link to real patients with matching genetic profiles. This model proves indispensable in drug discovery endeavors, facilitating the development of innovative targeted treatments for breast cancer. Its utilization spans from investigating small molecules and antibodies to refining cell-based therapies, enhancing the prospects of advancing effective interventions for breast cancer patients.
