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Primary Cells

C57BL/10J Mouse Bone Marrow Neutrophils

  • For research use only

Cat No.

ABC-TC3144
Product Type

Mouse Primary Cells
Cell Type

Neutrophil
Species

C57BL/10J Mouse
Growth Conditions

37 ℃, 5% CO2
Source Organ

Bone Marrow
Disease

Normal
Storage

Liquid Nitrogen

Mouse bone marrow neutrophils (MBMNEUCs) are derived from the tibias and femurs of pathogen-free laboratory adult mice.

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  • C57BL/10J Mouse Bone Marrow Neutrophils
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Home | Primary Cells | Animal Primary Cells | Mouse Primary cells | C57BL/10J Mouse Bone Marrow Neutrophils

Description

C57BL/10J Mouse Bone Marrow Neutrophils are innate immune effector cells in the bone marrow, belonging to the granulocyte lineage. They differentiate from stages common myeloid progenitor cells (CMPs) and granulocyte-monocyte progenitor cells (GMPs) in the bone marrow. Morphologically, mature neutrophils are round in shape with dense chromatin and are terminally differentiated cells. These cells express neutrophil elastase (NE). Their core functions encompass pathogen phagocytosis, release of reactive oxygen species (ROS), and formation of neutrophil extracellular traps (NETs), playing a crucial role in acute inflammatory responses. These cells are widely studied for their roles in neutrophil phenotype analysis, neutrophil interactions, and contributions to the inflammatory response in C57BL/10J mice, reflecting key mechanisms of innate immunity. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

C57BL/10J Mouse Bone Marrow Neutrophils, C57BL/10J BMNs, B10J BM Neutrophils
Species

C57BL/10J Mouse
Cat.No

ABC-TC3144
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Neutrophil
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Bone Marrow
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Mouse Primary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • C57BL/10J Mouse Bone Marrow Neutrophils can be used to explore the pathological mechanisms of infectious diseases (such as bacterial or fungal infections), autoimmune diseases (such as rheumatoid arthritis), and sepsis. These cells can also be used to explore the interaction between neutrophils and the tumor microenvironment, clarify their role in tumor growth and metastasis, and provide new ideas for the formulation of tumor immunotherapy strategies.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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