For research use only
| Cat No. | ABC-TC3187 |
| Product Type | Mouse Primary Cells |
| Cell Type | Endothelial |
| Species | C57BL/6 Mouse |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Dermal |
| Disease | Normal |
| Storage | Liquid Nitrogen |
C57BL/6 Mouse Dermal Microvascular Endothelial Cells support vascular biology, wound healing, and microcirculation research in preclinical studies.
C57BL/6 Mouse Dermal Microvascular Endothelial Cells are primary cells isolated from the skin of pathogen-free laboratory mice, serving as a reliable mouse model for microvascular research. Following primary culture, these cells are cryopreserved. These cells originate from the dermal capillary network, where they play essential roles in maintaining vascular barrier integrity, regulating angiogenesis, and mediating inflammatory responses. Studies have demonstrated their involvement in modeling dermatological pathologies such as psoriasis, diabetic ulcers, scleroderma, and cutaneous T-cell lymphoma. Dermal microvascular cell markers including VE-cadherin or CD31/PECAM-1. To preserve performance, repeated freezing and thawing should be avoided during culture. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | C57BL/6 Mouse Dermal Microvascular Endothelial Cells, Mouse Dermal Microvascular Endothelial Cells, Dermal Microvascular Endothelial Cells, Microvascular Endothelial Cells, MVECs, C57BL/6 Dermal MVECs |
| Species | C57BL/6 Mouse |
| Cat.No | ABC-TC3187 |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Endothelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Dermal |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Primary Cells |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
C57BL/6 Mouse Dermal Microvascular Endothelial Cells can be used as an in vitro model to study the pathogenesis of chronic skin inflammation in disease conditions such as psoriasis and diabetic ulceration. Researchers can delve into disease mechanisms by investigating molecular pathways like CXCL10-Toll-like receptor 4 (TLR4)-mediated neutrophil recruitment or hyperglycemia-induced eNOS uncoupling in diabetic ulcers. By elucidating pathways linked to pathological angiogenesis, microvascular leakage, and impaired perfusion.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).