Primary Cells

C57BL/6 Mouse Dermal Microvascular Endothelial Cells

  • For research use only

Cat No.

ABC-TC3187

Product Type

Mouse Primary Cells

Cell Type

Endothelial

Species

C57BL/6 Mouse

Growth Conditions

37 ℃, 5% CO2

Source Organ

Dermal

Disease

Normal

Storage

Liquid Nitrogen

C57BL/6 Mouse Dermal Microvascular Endothelial Cells support vascular biology, wound healing, and microcirculation research in preclinical studies.

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Description

C57BL/6 Mouse Dermal Microvascular Endothelial Cells are primary cells isolated from the skin of pathogen-free laboratory mice, serving as a reliable mouse model for microvascular research. Following primary culture, these cells are cryopreserved. These cells originate from the dermal capillary network, where they play essential roles in maintaining vascular barrier integrity, regulating angiogenesis, and mediating inflammatory responses. Studies have demonstrated their involvement in modeling dermatological pathologies such as psoriasis, diabetic ulcers, scleroderma, and cutaneous T-cell lymphoma. Dermal microvascular cell markers including VE-cadherin or CD31/PECAM-1. To preserve performance, repeated freezing and thawing should be avoided during culture. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

C57BL/6 Mouse Dermal Microvascular Endothelial Cells, Mouse Dermal Microvascular Endothelial Cells, Dermal Microvascular Endothelial Cells, Microvascular Endothelial Cells, MVECs, C57BL/6 Dermal MVECs

Species

C57BL/6 Mouse

Cat.No

ABC-TC3187

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Endothelial

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Dermal

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Mouse Primary Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • C57BL/6 Mouse Dermal Microvascular Endothelial Cells can be used as an in vitro model to study the pathogenesis of chronic skin inflammation in disease conditions such as psoriasis and diabetic ulceration. Researchers can delve into disease mechanisms by investigating molecular pathways like CXCL10-Toll-like receptor 4 (TLR4)-mediated neutrophil recruitment or hyperglycemia-induced eNOS uncoupling in diabetic ulcers. By elucidating pathways linked to pathological angiogenesis, microvascular leakage, and impaired perfusion.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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