C57BL/6 Mouse Pulmonary Artery Endothelial Cells

Description

C57BL/6 Mouse Pulmonary Artery Endothelial Cells, also known as Murine PAEC primary cells and derived from the Mouse pulmonary arterial endothelium, are obtained from the inner lining of pulmonary arteries in C57BL/6 mice. These cells are essential for maintaining vascular homeostasis, regulating blood flow, and mediating responses to hypoxia and inflammation. Pulmonary artery endothelial cells are widely used in research on pulmonary hypertension, thrombosis, and endothelial barrier function. They express endothelial markers such as CD31 and von Willebrand factor (vWF). They provide a valuable model for investigating vascular remodeling and endothelial signaling pathways. Repeated freeze-thaw cycles should be avoided in vitro to preserve cell viability and functional phenotype. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from mycoplasma, fungi, yeast, and bacteria.