For research use only
| Cat No. | ABC-TC0221 |
| Product Type | Cricetulus Griseus Lung Cell Lines |
| Cell Type | Fibroblast |
| Species | Cricetulus Griseus |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lung |
| Product Code | CCL16; CHD; Chinese Hamster Don; CHL-Don |
The DON cell line supports glioblastoma research, oncogenic signaling studies, and tumor progression analysis for translational applications.
DON cell line, also known as the CCL-16 cell line, is a spontaneously immortalized cell line originally isolated from the lung of 8-month-old male Cricetulus griseus. This cell line exhibits fibroblast-like morphology and adherent monolayer growth. DON cells are maintained in a humidified incubator at 37°C with 5% CO2 and propagated as a monolayer in Ham’s F-10 nutrient mixture supplemented with 10% fetal calf serum and antibiotics. These cells have a diploid karyotype with 2n=22 and are susceptible to vesicular stomatitis (Indiana strain) virus. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | CCL16; CHD; Chinese Hamster Don; CHL-Don |
| Species | Cricetulus Griseus |
| Cat.No | ABC-TC0221 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Fibroblast |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lung |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Cricetulus Griseus Lung Cell Lines |
DON cell line serves as a karyotypically stable model for studying spontaneous mutations in nucleotide transport systems, particularly thymidine uptake defects. They enable in vitro mutation rate quantification using fluctuation tests and membrane transport mechanism analysis through comparative autoradiography and kinetic uptake studies. For example, characterizing the specific impairment in facilitative thymidine transport in Tp-mutants advances research on somatic cell genetics and membrane physiology, supporting the development of strategies targeting nucleotide metabolism.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
