Tumor Cell Lines

DSL-6B/C2

  • For research use only

Cat No.

ABC-TC0225

Product Type

Rat Pancreas Cancer Cell Lines

Cell Type

Epithelial

Species

Rat

Growth Conditions

37 ℃, 5% CO2

Source Organ

Pancreas

Product Code

DSL-6B-C2; DSL6B/C2

DSL-6B/C2 is a pancreatic ductal cell line derived from the DSL-6 transplantable acinar cell carcinoma.

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Description

The DSL-6B/C2 is a pancreatic ductal cell line derived from the DSL-6 transplantable acinar cell carcinoma of a 2-year-old male syngeneic Lewis rat. This cell line exhibits epithelial-like morphology with irregular glandular structures, prominent nucleoli and adherent culture properties, and is recommended to be cultured in Waymouth’s MB 752/1 Medium supplemented with 10% Fetal Bovine Serum (FBS). DSL-6B/C2 expresses mucin and duct cell markers. The cell line is highly tumorigenic and metastatic in syngeneic Lewis rats, forming solid and partially cystic tumors composed of mixed squamous, mucinous, and glandular areas. Metastases occur in ductal tissues. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

DSL-6B-C2; DSL6B/C2

Species

Rat

Cat.No

ABC-TC0225

Product Category

Tumor Cell Lines

Size/Quantity

1 vial

Cell Type

Epithelial

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Pancreas

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Rat Pancreas Cancer Cell Lines

Application

  • DSL-6B/C2 cells serve as a syngeneic rat pancreatic ductal adenocarcinoma (PDAC) model to investigate tumor-stroma crosstalk and therapy resistance mechanisms. They enable in vitro chemotherapy screening and quantitative metastasis studies through analysis of TGF-β-mediated epithelial-mesenchymal transition (EMT). This system facilitates tumor microenvironment modeling in 3D organoids with intact stromal components and supports in vitro evaluation of potential therapeutic targets for aggressive pancreatic cancer.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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