HighQC™ Human Leukemia Cancer Stem Cell

Description

HighQC™ Human Leukemia Cancer Stem Cells are isolated from primary leukemic bone marrow samples and cultured under serum-free, stem cell–selective conditions to enrich for leukemia-initiating cells. These cells exhibit a small, round morphology with high nucleus-to-cytoplasm ratio and express classical LSC markers such as CD133, CD44, SSEA 3/4, Oct4. Functionally, they possess extensive self-renewal capacity, quiescence, and the ability to reconstitute leukemia in immunodeficient mouse models, making them essential for studying leukemogenesis and relapse. These cells often exhibit resistance to chemotherapy and contribute to disease persistence following treatment. HighQC™ Leukemia Cancer Stem Cells provide a reliable, reproducible in vitro system for exploring leukemic hierarchy, clonal evolution, and therapeutic response. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.