HighQC™ Human Pancreatic Cancer Stem Cell

Description

HighQC™ Human Pancreatic Cancer Stem Cells (CSCs) are derived from primary human pancreatic ductal adenocarcinoma (PDAC) tissue. These cells exhibit typical stem cell epithelial morphology, forming closely packed, rounded colonies in adherent culture. They co-express surface markers CD24, CD44. PCSCs also exhibit high aldehyde dehydrogenase 1 (ALDH1) activity and overexpression of stemness-associated transcription factors such as NANOG, SOX2, and OCT4. These characteristics reflect functional hallmarks of human pancreatic CSCs, including therapy resistance, dormancy, and metastatic potential. Their invasive, slow-cycling nature mirrors the behavior of cancer stem cells in vivo, making them a faithful model for aggressive PDAC research. They support both 2D and spheroid culture systems, offering flexibility in experimental design for translational studies. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.