Human Fetal Liver Cells Mononuclear Cells 13-24 Weeks Gestation

Description

Human Fetal Liver Mononuclear Cells (13–24 Weeks Gestation) are isolated from mid-trimester fetal liver tissue, during a critical period of hematopoietic and immune system development. This mononuclear cell population is highly heterogeneous and is predominantly composed of hematopoietic stem and progenitor cells (HSCs/HPCs), erythroid progenitors, and hepatoblasts, with smaller proportions of early lymphoid cells and myeloid-lineage cells. Morphologically, the majority of fetal liver mononuclear cells display round to oval nuclei with a high nuclear-to-cytoplasmic ratio, characteristic of immature hematopoietic progenitors and erythroid precursors. Functionally, immune-related subsets within this mononuclear fraction contribute to innate immune responses, including phagocytic activity, antigen processing, and antigen presentation. These cells support experimental studies of human fetal liver biology and facilitate analysis of fetal liver mononuclear cell markers for mid-gestation hematopoietic and immune research. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.