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Primary Cells

Human Keratinocytes, Adult, Diabetic Donor

  • For research use only

Cat No.

ABC-TC3031
Product Type

Keratinocyte
Cell Type

Keratinocyte
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Skin
Disease

Diabetic
Storage

Liquid Nitrogen

Utilize Adult Diabetic Donor Keratinocytes for investigating wound healing impairments, insulin signaling, and diabetic skin pathophysiology.

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  • Human Keratinocytes, Adult, Diabetic Donor
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Home | Primary Cells | Human Primary Cells | Others | Human Keratinocytes, Adult, Diabetic Donor

Description

Human Keratinocytes, Adult, Diabetic Donor, are isolated from the epidermal layer of skin tissue from adult donors with confirmed type 2 diabetes mellitus (T2DM). These primary cells, cryopreserved at early passage, exhibit epithelial morphology and limited proliferative capacity in vitro. In diabetic skin, keratinocytes exhibit altered proliferation, differentiation, and impaired wound repair capacity—key features implicated in chronic wound pathology. They are characterized by decreased expression of stemness markers (e.g., K19, β1-integrin). Due to their metabolic and inflammatory alterations, they provide a valuable in vitro model for studying skin complications associated with diabetes. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

Human Keratinocytes, Adult, Diabetic Donor, Adult diabetic human keratinocytes, Human diabetic keratinocytes
Species

Human
Cat.No

ABC-TC3031
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Keratinocyte
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Skin
Disease

Diabetic
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Keratinocyte
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • These diabetic keratinocytes are ideal for exploring delayed wound healing mechanisms, testing regenerative therapies, and investigating epidermal responses to hyperglycemic stress. They support studies in diabetic skin disease research, such as diabetic foot ulcers, skin barrier dysfunction, and keratinocyte-microbiome interactions. They can also be employed in transcriptomic and proteomic profiling to identify biomarkers linked to diabetic skin dysfunction.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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